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Semaglutide

A GLP-1 receptor agonist with a C18 fatty diacid chain enabling long half-life. Extensively studied in metabolic, appetite regulation, and cardiovascular preclinical models.
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Description

Semaglutide is a glucagon-like peptide-1 (GLP-1) analogue with 94% structural homology to native human GLP-1. Its C18 fatty diacid chain enables reversible albumin binding, conferring a half-life of approximately 7 days in vivo. It has become one of the most researched metabolic peptides globally, featuring in numerous peer-reviewed studies on insulin secretion, appetite regulation, hepatic lipogenesis, and cardiovascular risk reduction. Research-grade semaglutide is produced via solid-phase peptide synthesis and purified to ≥99.4% purity as confirmed by reversed-phase HPLC and ESI-MS.

Molecular Formula C₁₈₄H₂₉₁N₄₅O₅₉
Molecular Weight 4113.58 g/mol
Sequence 34 amino acid GLP-1 analogue with C18 fatty acid chain
Purity ≥99.4% (HPLC)
Format Lyophilized powder
Appearance White powder
Solubility Sterile water (pH 7.4)
Storage −20°C long-term
Batch No CB-2024-SEMA-03
Testing HPLC + ESI-MS + Endotoxin
Origin Solid-phase synthesis

Additional information

Size

10 mg, 2 mg, 5 mg

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